Product Data Sheet

FP0429

Catalog No. A61894

main product photo
FP0429 is a potent full agonist of the metabotropic glutamate receptor 4 (mGlu4) and a partial agonist of metabotropic glutamate receptor 8 (mGlu8), exhibiting EC50 values of 48.3 μM and 56.2 μM, respectively. This compound is valuable for research involving glutamatergic signaling pathways, particularly in the context of neurodegenerative diseases, mood disorders, and other neurological conditions. Its unique pharmacological profile makes it a useful tool for studying the role of mGlu receptors in synaptic transmission and neuronal plasticity.
Chemical Information
Catalog NumA61894
M. Wt272.21
FormulaC10H12N2O7
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.870860-41-6
Synonyms
SMILESO=C(O)[C@H]1N(C[C@@](N)(C1)C(O)=O)C(/C=C/C(O)=O)=O
Biological Activity
DescriptionFP0429 is a potent full agonist of the metabotropic glutamate receptor 4 (mGlu4) and a partial agonist of metabotropic glutamate receptor 8 (mGlu8), exhibiting EC50 values of 48.3 μM and 56.2 μM, respectively. This compound is valuable for research involving glutamatergic signaling pathways, particularly in the context of neurodegenerative diseases, mood disorders, and other neurological conditions. Its unique pharmacological profile makes it a useful tool for studying the role of mGlu receptors in synaptic transmission and neuronal plasticity.
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SHIPPING AND STORAGE
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