Product Data Sheet
VU0366248
Catalog No. A61902
VU0366248 is a negative allosteric modulator of the metabotropic glutamate receptor type 5 (mGlu5). This compound inhibits mGlu5 receptor signaling, offering potential therapeutic applications in disorders associated with glutamate dysregulation, such as anxiety, depression, and schizophrenia. Researchers can utilize VU0366248 to investigate the functional role of mGlu5 in synaptic plasticity and to explore its implications in neuropharmacology.
Chemical Information
| Catalog Num | A61902 |
|---|---|
| M. Wt | 292.67 |
| Formula | C14H7ClF2N2O |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1243310-20-4 |
| Synonyms | |
| SMILES | O=C(C1=CC(F)=CC(C#N)=C1)NC2=CC=CC(Cl)=C2F |
Biological Activity
| Description | VU0366248 is a negative allosteric modulator of the metabotropic glutamate receptor type 5 (mGlu5). This compound inhibits mGlu5 receptor signaling, offering potential therapeutic applications in disorders associated with glutamate dysregulation, such as anxiety, depression, and schizophrenia. Researchers can utilize VU0366248 to investigate the functional role of mGlu5 in synaptic plasticity and to explore its implications in neuropharmacology. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
