Product Data Sheet
LY2934747
Catalog No. A61919
LY2934747 is a selective dual agonist for the mGlu2 and mGlu3 receptors, demonstrating blood-brain barrier permeability. With Ki values of 260 nM and 177 nM and EC50 values of 8.4 nM and 62.4 nM for human receptors, it effectively mediates signaling pathways associated with these targets. LY2934747 displays antipsychotic and analgesic activities in vivo, making it a valuable tool for research into psychosis and pain management.
Chemical Information
| Catalog Num | A61919 |
|---|---|
| M. Wt | 211.22 |
| Formula | C10H13NO4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1448707-43-4 |
| Synonyms | |
| SMILES | C(O)(=O)[C@H]1[C@@]2(C3(C[C@](C(O)=O)(N)[C@@]21[H])CC3)[H] |
Biological Activity
| Description | LY2934747 is a selective dual agonist for the mGlu2 and mGlu3 receptors, demonstrating blood-brain barrier permeability. With Ki values of 260 nM and 177 nM and EC50 values of 8.4 nM and 62.4 nM for human receptors, it effectively mediates signaling pathways associated with these targets. LY2934747 displays antipsychotic and analgesic activities in vivo, making it a valuable tool for research into psychosis and pain management. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
