Product Data Sheet

Spantide II

Catalog No. A61983

main product photo
Spantide II is a potent neurokinin-1 receptor (NK-1R) antagonist, functioning as an undecapeptide analog of substance P. By binding to NK-1R, Spantide II effectively inhibits the proinflammatory activities associated with substance P. This reagent is valuable for research into inflammatory skin disorders, including psoriasis and contact dermatitis, contributing to the understanding of neurogenic inflammation.
Chemical Information
Catalog NumA61983
M. Wt1668.76
FormulaC86H104Cl2N18O13
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.129176-97-2
Synonyms
SMILESC([C@H](C(N[C@H](C(N[C@H](CC=1C=2C(NC1)=CC=CC2)C(N[C@H](C(N[C@@H](CCCC)C(N)=O)=O)CC(C)C)=O)=O)CC3=CC=CC=C3)=O)NC([C@@H](NC([C@@H](CC4=CC(Cl)=C(Cl)C=C4)NC(=O)[C@H]5N(C([C@@H](NC(=O)[C@H]6N(C([C@@H](CCCCNC(=O)C=7C=CC=NC7)N)=O)CCC6)CC=8C=CC=NC8)=O)CCC5)=O)CC(N)=O)=O)C=9C=%10C(NC9)=CC=CC%10
Biological Activity
DescriptionSpantide II is a potent neurokinin-1 receptor (NK-1R) antagonist, functioning as an undecapeptide analog of substance P. By binding to NK-1R, Spantide II effectively inhibits the proinflammatory activities associated with substance P. This reagent is valuable for research into inflammatory skin disorders, including psoriasis and contact dermatitis, contributing to the understanding of neurogenic inflammation.
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.