Product Data Sheet

Hemokinin 1 (mouse)

Catalog No. A61991

main product photo
Hemokinin 1 (mouse) is a selective agonist of the neurokinin-1 receptor (NK1R), exhibiting a Ki value of 0.175 nM for mouse NK1R. This compound demonstrates a much lower affinity for the human NK2 receptor, with a Ki of 560 nM. Hemokinin 1 is primarily utilized in research applications aimed at studying pain modulation, inflammatory processes, and neurogenic signaling pathways involving the NK1 receptor.
Chemical Information
Catalog NumA61991
M. Wt1413.65
FormulaC61H100N22O15S
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.208041-90-1
Synonyms
SMILESCSCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CO)NC(=O)[C@@H](N)CCCNC(N)=N)[C@@H](C)O)C(N)=O
Biological Activity
DescriptionHemokinin 1 (mouse) is a selective agonist of the neurokinin-1 receptor (NK1R), exhibiting a Ki value of 0.175 nM for mouse NK1R. This compound demonstrates a much lower affinity for the human NK2 receptor, with a Ki of 560 nM. Hemokinin 1 is primarily utilized in research applications aimed at studying pain modulation, inflammatory processes, and neurogenic signaling pathways involving the NK1 receptor.
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SHIPPING AND STORAGE
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