Product Data Sheet
Nolpitantium
Catalog No. A62010
Nolpitantium is a potent and selective competitive antagonist of the tachykinin NK1 receptor. By inhibiting NK1 receptor activation, Nolpitantium effectively blocks the excitability of rat thalamic neurons in response to nociceptive stimulation. This compound is valuable for research into pain mechanisms and the role of neurokinin signaling in various neurophysiological processes.
Chemical Information
| Catalog Num | A62010 |
|---|---|
| M. Wt | 656.12 |
| Formula | C37H45Cl3N2O2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 153050-21-6 |
| Synonyms | SR140333 |
| SMILES | O=C(N1C[C@@](CC[N+]2(CC3)CCC3(C4=CC=CC=C4)CC2)(C5=CC=C(Cl)C(Cl)=C5)CCC1)CC6=CC=CC(OC(C)C)=C6.[Cl-] |
Biological Activity
| Description | Nolpitantium is a potent and selective competitive antagonist of the tachykinin NK1 receptor. By inhibiting NK1 receptor activation, Nolpitantium effectively blocks the excitability of rat thalamic neurons in response to nociceptive stimulation. This compound is valuable for research into pain mechanisms and the role of neurokinin signaling in various neurophysiological processes. |
|---|
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Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
