Product Data Sheet

[D-Trp2,7,9] Substance P

Catalog No. A62028

main product photo
[D-Trp2,7,9] Substance P is a tachykinin antagonist primarily targeting neurokinin receptors. It exhibits Ki values of 1 μM, 1.3 μM, and approximately 9 μM for NK-1, NK-2, and NK-3 receptors, respectively. This compound is utilized in research applications focused on modulating pain, inflammation, and neurogenic responses. Its ability to selectively block neurokinin receptor activity makes it a valuable tool for exploring tachykinin-related biological processes.
Chemical Information
Catalog NumA62028
M. Wt1604.92
FormulaC80H109N21O13S
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.100930-11-8
Synonyms
SMILESCSCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](N)CCCNC(N)=N)C(N)=O
Biological Activity
Description[D-Trp2,7,9] Substance P is a tachykinin antagonist primarily targeting neurokinin receptors. It exhibits Ki values of 1 μM, 1.3 μM, and approximately 9 μM for NK-1, NK-2, and NK-3 receptors, respectively. This compound is utilized in research applications focused on modulating pain, inflammation, and neurogenic responses. Its ability to selectively block neurokinin receptor activity makes it a valuable tool for exploring tachykinin-related biological processes.
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SHIPPING AND STORAGE
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