Product Data Sheet

Maropitant-d3

Catalog No. A62034

main product photo
Maropitant-d3 is a deuterium-labeled derivative of Maropitant, a selective neurokinin (NK1) receptor antagonist. This compound functions by inhibiting the binding of substance P in the emetic center and the chemoreceptor trigger zone (CRTZ), showcasing significant efficacy in the prevention of vomiting. Maropitant-d3 is valuable in chemical research requiring stable isotopes for the study of pharmacokinetics and metabolism of NK1 receptor antagonists.
Chemical Information
Catalog NumA62034
M. Wt471.69
FormulaC32H37D3N2O
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2124295-52-7
Synonyms
SMILESCC(C)(C)C1=CC=C(OC([2H])([2H])[2H])C(CN[C@@H]2[C@H](C(C3=CC=CC=C3)C4=CC=CC=C4)N5CCC2CC5)=C1
Biological Activity
DescriptionMaropitant-d3 is a deuterium-labeled derivative of Maropitant, a selective neurokinin (NK1) receptor antagonist. This compound functions by inhibiting the binding of substance P in the emetic center and the chemoreceptor trigger zone (CRTZ), showcasing significant efficacy in the prevention of vomiting. Maropitant-d3 is valuable in chemical research requiring stable isotopes for the study of pharmacokinetics and metabolism of NK1 receptor antagonists.
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SHIPPING AND STORAGE
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