Product Data Sheet

[Tyr6,D-Phe7,D-His9]-Substance P (6-11)

Catalog No. A62035

main product photo
[Tyr6,D-Phe7,D-His9]-Substance P (6-11) is a potent antagonist of the tachykinin NK1 receptor. This compound effectively inhibits hyperalgesia induced by histamine, making it valuable for research into pain pathways and the mechanisms of nociception. Its application extends to studies investigating the role of tachykinins in various biological processes and pain modulation.
Chemical Information
Catalog NumA62035
M. Wt856.04
FormulaC44H57N9O7S
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.145194-26-9
Synonyms
SMILESCSCC[C@@H](C(N)=O)NC([C@H](CC(C)C)NC([C@@H](CC1=CN=CN1)NC([C@@H](NC([C@H](NC([C@@H](N)CC2=CC=C(C=C2)O)=O)CC3=CC=CC=C3)=O)CC4=CC=CC=C4)=O)=O)=O
Biological Activity
Description[Tyr6,D-Phe7,D-His9]-Substance P (6-11) is a potent antagonist of the tachykinin NK1 receptor. This compound effectively inhibits hyperalgesia induced by histamine, making it valuable for research into pain pathways and the mechanisms of nociception. Its application extends to studies investigating the role of tachykinins in various biological processes and pain modulation.
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