Product Data Sheet
Men 10376
Catalog No. A62038
Men 10376 is a selective tachykinin NK-2 receptor antagonist that exhibits a Ki value of 4.4 μM for the rat small intestine NK-2 receptor. This compound demonstrates significant inhibition of NK-2 receptor-mediated biological activities, making it a valuable tool for research into neurokinin signaling pathways. It is applicable in studies focused on gastrointestinal motility, pain modulation, and other physiological processes mediated by tachykinins.
Chemical Information
| Catalog Num | A62038 |
|---|---|
| M. Wt | 1081.22 |
| Formula | C57H68N12O10 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 135306-85-3 |
| Synonyms | Neurokinin-2 receptor antagonist |
| SMILES | C([C@H](C(N[C@H](CC=1C=2C(NC1)=CC=CC2)C(N[C@@H](CCCCN)C(N)=O)=O)=O)NC([C@@H](NC([C@@H](CC=3C=4C(NC3)=CC=CC4)NC([C@H](CC5=CC=C(O)C=C5)NC([C@H](CC(O)=O)N)=O)=O)=O)C(C)C)=O)C=6C=7C(NC6)=CC=CC7 |
Biological Activity
| Description | Men 10376 is a selective tachykinin NK-2 receptor antagonist that exhibits a Ki value of 4.4 μM for the rat small intestine NK-2 receptor. This compound demonstrates significant inhibition of NK-2 receptor-mediated biological activities, making it a valuable tool for research into neurokinin signaling pathways. It is applicable in studies focused on gastrointestinal motility, pain modulation, and other physiological processes mediated by tachykinins. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
