Product Data Sheet

[Nle11]-Substance P

Catalog No. A62052

main product photo
[Nle11]-Substance P is an agonist of neurokinin receptors, designed to circumvent the oxidation issues associated with methionine in natural Substance P. This analog exhibits enhanced stability and retains biological activity, making it suitable for research studies focused on pain modulation, neurogenic inflammation, and neuropsychiatric disorders. Its application in various in vitro and in vivo models supports investigations into neurokinin signaling pathways and their implications in therapeutic interventions.
Chemical Information
Catalog NumA62052
M. Wt1329.59
FormulaC64H100N18O13
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.57462-42-7
Synonyms
SMILESC([C@@H](NC(=O)[C@H]1N(C([C@H](CCCNC(=N)N)N)=O)CCC1)CCCCN)(=O)N2[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC3=CC=CC=C3)C(N[C@@H](CC4=CC=CC=C4)C(NCC(N[C@H](C(N[C@@H](CCCC)C(N)=O)=O)CC(C)C)=O)=O)=O)=O)CCC(N)=O)=O)CCC(N)=O)=O)CCC2
Biological Activity
Description[Nle11]-Substance P is an agonist of neurokinin receptors, designed to circumvent the oxidation issues associated with methionine in natural Substance P. This analog exhibits enhanced stability and retains biological activity, making it suitable for research studies focused on pain modulation, neurogenic inflammation, and neuropsychiatric disorders. Its application in various in vitro and in vivo models supports investigations into neurokinin signaling pathways and their implications in therapeutic interventions.
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SHIPPING AND STORAGE
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