Product Data Sheet

L 363851

Catalog No. A62069

main product photo
L 363851 is a potent agonist of the neurokinin 2 receptor, demonstrating a significant contractile response in tracheal smooth muscle tissue devoid of epithelium with an IC50 value of 3.2 nM. Additionally, it stimulates phosphoinositide hydrolysis with an IC50 of 36 μM. This compound is valuable for research applications focusing on respiratory physiology and neurogenic inflammation.
Chemical Information
Catalog NumA62069
M. Wt749.92
FormulaC38H51N7O7S
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.100807-53-2
Synonyms
SMILESCSCC[C@@H](C(N)=O)NC([C@@H](N1C([C@@H](CC1)NC([C@H](CC2=CC=CC=C2)NC([C@@H](NC([C@@H]3CCC(N3)=O)=O)CC4=CC=CC=C4)=O)=O)=O)CC(C)C)=O
Biological Activity
DescriptionL 363851 is a potent agonist of the neurokinin 2 receptor, demonstrating a significant contractile response in tracheal smooth muscle tissue devoid of epithelium with an IC50 value of 3.2 nM. Additionally, it stimulates phosphoinositide hydrolysis with an IC50 of 36 μM. This compound is valuable for research applications focusing on respiratory physiology and neurogenic inflammation.
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