Product Data Sheet

CP 122721 hydrochloride

Catalog No. A62080

main product photo
CP 122721 hydrochloride is a potent, selective non-peptide antagonist of the neurokinin NK1 receptor, exhibiting a pIC50 of 9.8 in human NK1 receptor assays using IM-9 cells. This compound demonstrates significant anxiolytic and antidepressant-like properties, making it a valuable tool for research in anxiety and mood disorder studies. It is suitable for investigating the role of NK1 receptors in neuropsychiatric conditions.
Chemical Information
Catalog NumA62080
M. Wt453.33
FormulaC20H25Cl2F3N2O2
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.145877-52-7
Synonyms
SMILESCOC1=C(C=C(C=C1)OC(F)(F)F)CN[C@H]2CCCN[C@H]2C3=CC=CC=C3.Cl.Cl
Biological Activity
DescriptionCP 122721 hydrochloride is a potent, selective non-peptide antagonist of the neurokinin NK1 receptor, exhibiting a pIC50 of 9.8 in human NK1 receptor assays using IM-9 cells. This compound demonstrates significant anxiolytic and antidepressant-like properties, making it a valuable tool for research in anxiety and mood disorder studies. It is suitable for investigating the role of NK1 receptors in neuropsychiatric conditions.
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