Product Data Sheet

Acetylaszonalenin

Catalog No. A62095

main product photo
Acetylaszonalenin is a prenylated indole derivative that acts as a neurokinin-1 (NK1) receptor antagonist. This fungal metabolite demonstrates significant inhibition of [3H]-substance P binding to human astrocytoma cells, with a Ki value of 170 μM. Acetylaszonalenin is applicable in research exploring neurokinin signaling and its role in neuroinflammation and related neurological disorders.
Chemical Information
Catalog NumA62095
M. Wt415.48
FormulaC25H25N3O3
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.42230-55-7
SynonymsLL-S490β
SMILESO=C1N2[C@@]([H])(C(NC3=CC=CC=C13)=O)C[C@]4([C@@]2(N(C5=C4C=CC=C5)C(C)=O)[H])C(C)(C=C)C
Biological Activity
DescriptionAcetylaszonalenin is a prenylated indole derivative that acts as a neurokinin-1 (NK1) receptor antagonist. This fungal metabolite demonstrates significant inhibition of [3H]-substance P binding to human astrocytoma cells, with a Ki value of 170 μM. Acetylaszonalenin is applicable in research exploring neurokinin signaling and its role in neuroinflammation and related neurological disorders.
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