Product Data Sheet

Substance P (2-11)

Catalog No. A62096

main product photo
Substance P (2-11) is a peptide fragment of Substance P that primarily targets neurokinin receptors. It exhibits contractile activity in guinea pig ileum, indicating its potential role in gastrointestinal motility. Additionally, Substance P (2-11) has been shown to inhibit the permeation of tritiated Substance P across blood-brain barrier endothelial cell monolayers, making it relevant for research in neurobiology and drug delivery.
Chemical Information
Catalog NumA62096
M. Wt1191.44
FormulaC57H86N14O12S
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.53749-61-4
Synonyms
SMILESC([C@@H](NC(=O)[C@@H]1CCCN1)CCCCN)(=O)N2[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC3=CC=CC=C3)C(N[C@@H](CC4=CC=CC=C4)C(NCC(N[C@H](C(N[C@@H](CCSC)C(N)=O)=O)CC(C)C)=O)=O)=O)=O)CCC(N)=O)=O)CCC(N)=O)=O)CCC2
Biological Activity
DescriptionSubstance P (2-11) is a peptide fragment of Substance P that primarily targets neurokinin receptors. It exhibits contractile activity in guinea pig ileum, indicating its potential role in gastrointestinal motility. Additionally, Substance P (2-11) has been shown to inhibit the permeation of tritiated Substance P across blood-brain barrier endothelial cell monolayers, making it relevant for research in neurobiology and drug delivery.
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SHIPPING AND STORAGE
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