Product Data Sheet

(D-Pro2,D-Trp6,8,Nle10)-Neurokinin B

Catalog No. A62105

main product photo
(D-Pro2,D-Trp6,8,Nle10)-Neurokinin B is a competitive antagonist of Neurokinin B, primarily targeting the Neurokinin Receptor, with a pA2 value of 5.5. This compound selectively inhibits Neurokinin B activity without affecting Substance P or Neurokinin A, making it valuable for studies of neuromodulation and neuropeptide signaling. Its ability to modulate neurokinin pathways is relevant for research in neurobiology and potential therapeutic applications related to pain and inflammatory responses.
Chemical Information
Catalog NumA62105
M. Wt1326.50
FormulaC67H87N15O14
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.109212-72-8
Synonyms
SMILESCCCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H]1CCCN1C(=O)[C@@H](N)CC(O)=O)C(C)C)C(N)=O
Biological Activity
Description(D-Pro2,D-Trp6,8,Nle10)-Neurokinin B is a competitive antagonist of Neurokinin B, primarily targeting the Neurokinin Receptor, with a pA2 value of 5.5. This compound selectively inhibits Neurokinin B activity without affecting Substance P or Neurokinin A, making it valuable for studies of neuromodulation and neuropeptide signaling. Its ability to modulate neurokinin pathways is relevant for research in neurobiology and potential therapeutic applications related to pain and inflammatory responses.
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SHIPPING AND STORAGE
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