Product Data Sheet
GSK172981
Catalog No. A62127
GSK172981 is a potent antagonist of the tachykinin NK3 receptor, demonstrating pKi values of 7.7 and 7.8 for human and native guinea pig NK3 receptors, respectively. This compound exhibits brain penetrance and is primarily utilized in research focused on schizophrenia, providing valuable insights into neurokinin signaling pathways and their implications in psychiatric disorders.
Chemical Information
| Catalog Num | A62127 |
|---|---|
| M. Wt | 411.47 |
| Formula | C26H22FN3O |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1133705-99-3 |
| Synonyms | |
| SMILES | O=C(N[C@H](C1=CC=CC=C1)C2CC2)C3=C(C(C4=CC=CC(F)=C4)=NC5=CC=CC=C35)N |
Biological Activity
| Description | GSK172981 is a potent antagonist of the tachykinin NK3 receptor, demonstrating pKi values of 7.7 and 7.8 for human and native guinea pig NK3 receptors, respectively. This compound exhibits brain penetrance and is primarily utilized in research focused on schizophrenia, providing valuable insights into neurokinin signaling pathways and their implications in psychiatric disorders. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
