Neuropeptide FF
Catalog No. A62166

Neuropeptide FF (NPFF) functions as an agonist for the NPFF1 and NPFF2 receptors, exhibiting Ki values of 2.82 nM and 0.21 nM, respectively. This octapeptide plays a crucial role in mediating various physiological processes, including the modulation of pain, opioids, autonomic function, and neuroendocrine responses. It is involved in the regulation of memory and the control of food and water intake, while also demonstrating significant antiopioid and analgesic properties. Neuropeptide FF is particularly relevant for research into opioid tolerance, morphine-induced analgesia, abstinence syndrome, and pain-related conditions, including inflammatory and neuropathic pain.
Chemical Information
| Catalog Num | A62166 |
|---|---|
| M. Wt | 1081.27 |
| Formula | C54H76N14O10 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 99566-27-5 |
| Synonyms | NPFF |
| SMILES | CC(C)C[C@H](NC(=O)[C@@H](N)Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCC(N)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccccc1)C(N)=O |
Biological Activity
| Description | Neuropeptide FF (NPFF) functions as an agonist for the NPFF1 and NPFF2 receptors, exhibiting Ki values of 2.82 nM and 0.21 nM, respectively. This octapeptide plays a crucial role in mediating various physiological processes, including the modulation of pain, opioids, autonomic function, and neuroendocrine responses. It is involved in the regulation of memory and the control of food and water intake, while also demonstrating significant antiopioid and analgesic properties. Neuropeptide FF is particularly relevant for research into opioid tolerance, morphine-induced analgesia, abstinence syndrome, and pain-related conditions, including inflammatory and neuropathic pain. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.


