Product Data Sheet
NPFF1-R antagonist 1
Catalog No. A62168
NPFF1-R antagonist 1 is a potent antagonist of the neuropeptide FF (NPFF) receptor, specifically targeting the NPFF1-R subtype. This compound, a piperidine analogue, demonstrates a selective blockade with a Ki of 211 nM for NPFF1-R and 3270 nM for NPFF2-R, indicating a remarkable 15-fold selectivity. It is suitable for research applications exploring neuropeptide signaling pathways and potential neurological disorders linked to NPFF receptor activity.
Chemical Information
| Catalog Num | A62168 |
|---|---|
| M. Wt | 560.77 |
| Formula | C37H44N4O |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 3057753-40-6 |
| Synonyms | |
| SMILES | O=C(CN1CCC(CC2=CC=CC=C2)CC1)NCC3(CCN(CC4=CC=CC=C4)CC3)NC5=C(C=CC=C6)C6=CC=C5 |
Biological Activity
| Description | NPFF1-R antagonist 1 is a potent antagonist of the neuropeptide FF (NPFF) receptor, specifically targeting the NPFF1-R subtype. This compound, a piperidine analogue, demonstrates a selective blockade with a Ki of 211 nM for NPFF1-R and 3270 nM for NPFF2-R, indicating a remarkable 15-fold selectivity. It is suitable for research applications exploring neuropeptide signaling pathways and potential neurological disorders linked to NPFF receptor activity. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
