Product Data Sheet

AC-099 hydrochloride

Catalog No. A62169

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AC-099 hydrochloride is a selective full agonist of the neuropeptide FF receptor 2 (NPFF2R) with an EC50 of 1189 nM, and a partial agonist of NPFF1R with an EC50 of 2370 nM. This compound has demonstrated the ability to attenuate hypersensitivity induced by spinal nerve ligation in rat models. AC-099 hydrochloride is valuable for research focusing on pain modulation and the neuropeptide signaling pathways associated with nociception.
Chemical Information
Catalog NumA62169
M. Wt301.10
FormulaC9H9Cl2F3N4
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.849335-07-5
Synonyms
SMILESFC(C1=CC(/C=N/NC(N)=N)=CC=C1Cl)(F)F.[H]Cl
Biological Activity
DescriptionAC-099 hydrochloride is a selective full agonist of the neuropeptide FF receptor 2 (NPFF2R) with an EC50 of 1189 nM, and a partial agonist of NPFF1R with an EC50 of 2370 nM. This compound has demonstrated the ability to attenuate hypersensitivity induced by spinal nerve ligation in rat models. AC-099 hydrochloride is valuable for research focusing on pain modulation and the neuropeptide signaling pathways associated with nociception.
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