Product Data Sheet
AC-099
Catalog No. A62174
AC-099 is a selective agonist for the neuropeptide FF receptor 2 (NPFF2R) with an EC50 of 1189 nM and a partial agonist for NPFF1R, exhibiting an EC50 of 2370 nM. This compound demonstrates significant potential in modulating pain responses, as evidenced by its ability to attenuate spinal nerve ligation-induced hypersensitivity in rat models. AC-099 serves as a valuable tool in pain research and for exploring the roles of NPFF receptors in the central nervous system.
Chemical Information
| Catalog Num | A62174 |
|---|---|
| M. Wt | 264.63 |
| Formula | C9H8ClF3N4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 849459-88-7 |
| Synonyms | |
| SMILES | FC(C1=CC(/C=N/NC(N)=N)=CC=C1Cl)(F)F |
Biological Activity
| Description | AC-099 is a selective agonist for the neuropeptide FF receptor 2 (NPFF2R) with an EC50 of 1189 nM and a partial agonist for NPFF1R, exhibiting an EC50 of 2370 nM. This compound demonstrates significant potential in modulating pain responses, as evidenced by its ability to attenuate spinal nerve ligation-induced hypersensitivity in rat models. AC-099 serves as a valuable tool in pain research and for exploring the roles of NPFF receptors in the central nervous system. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
