Product Data Sheet
SHA 68
Catalog No. A62175
SHA 68 is a potent and selective non-peptide antagonist of the neuropeptide S receptor (NPSR), demonstrating IC50 values of 22.0 nM for NPSR Asn107 and 23.8 nM for NPSR Ile107. This compound exhibits limited blood-brain barrier penetration, making it suitable for research on peripheral applications and neuralgia. SHA 68 is valuable for studying the physiological roles of neuropeptide S and its potential implications in pain modulation and neurobiology.
Chemical Information
| Catalog Num | A62175 |
|---|---|
| M. Wt | 445.49 |
| Formula | C26H24FN3O3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 847553-89-3 |
| Synonyms | |
| SMILES | O=C(N1CC2N(C(OC2(C3=CC=CC=C3)C4=CC=CC=C4)=O)CC1)NCC5=CC=C(F)C=C5 |
Biological Activity
| Description | SHA 68 is a potent and selective non-peptide antagonist of the neuropeptide S receptor (NPSR), demonstrating IC50 values of 22.0 nM for NPSR Asn107 and 23.8 nM for NPSR Ile107. This compound exhibits limited blood-brain barrier penetration, making it suitable for research on peripheral applications and neuralgia. SHA 68 is valuable for studying the physiological roles of neuropeptide S and its potential implications in pain modulation and neurobiology. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
