Product Data Sheet
Buccalin
Catalog No. A62180
Buccalin is a neuropeptide that primarily targets synaptic transmission at the neuromuscular junction. It effectively reduces the amplitude of motor neuron-induced muscle contractions when externally administered, acting presynaptically without influencing the rate of muscle relaxation. Buccalin diminishes excitatory junction potentials at the ARC while preserving the contractile response elicited directly through acetylcholine. This selective modulation makes it a valuable tool for research on synaptic mechanisms and neuropeptide function in neuromuscular signaling.
Chemical Information
| Catalog Num | A62180 |
|---|---|
| M. Wt | 1053.19 |
| Formula | C45H72N12O15S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 116786-35-7 |
| Synonyms | |
| SMILES | [C@H](CC1=CC=CC=C1)(C(N[C@H](C(NCC(NCC(N[C@@H](CC(C)C)C(N)=O)=O)=O)=O)CO)=O)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CN)=O)CCSC)=O)CC(O)=O)=O)CO)=O)CC(C)C)=O)C)=O |
Biological Activity
| Description | Buccalin is a neuropeptide that primarily targets synaptic transmission at the neuromuscular junction. It effectively reduces the amplitude of motor neuron-induced muscle contractions when externally administered, acting presynaptically without influencing the rate of muscle relaxation. Buccalin diminishes excitatory junction potentials at the ARC while preserving the contractile response elicited directly through acetylcholine. This selective modulation makes it a valuable tool for research on synaptic mechanisms and neuropeptide function in neuromuscular signaling. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
