Product Data Sheet
BIBO3304
Catalog No. A62183
BIBO3304 is a selective antagonist of the neuropeptide Y (NPY) Y1 receptor, exhibiting subnanomolar affinity with IC50 values of 0.38 nM for the human receptor and 0.72 nM for the rat receptor. This compound serves as a valuable tool for investigating the role of NPY signaling in various biological processes, including appetite regulation and anxiety-related behaviors. Its oral bioavailability makes it suitable for in vivo studies in pharmacological research and neurobiology.
Chemical Information
| Catalog Num | A62183 |
|---|---|
| M. Wt | 643.66 |
| Formula | C31H36F3N7O5 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 191868-14-1 |
| Synonyms | |
| SMILES | O=C(N[C@@H](C(NCC1=CC=C(CNC(N)=O)C=C1)=O)CCCNC(N)=N)C(C2=CC=CC=C2)C3=CC=CC=C3.O=C(O)C(F)(F)F |
Biological Activity
| Description | BIBO3304 is a selective antagonist of the neuropeptide Y (NPY) Y1 receptor, exhibiting subnanomolar affinity with IC50 values of 0.38 nM for the human receptor and 0.72 nM for the rat receptor. This compound serves as a valuable tool for investigating the role of NPY signaling in various biological processes, including appetite regulation and anxiety-related behaviors. Its oral bioavailability makes it suitable for in vivo studies in pharmacological research and neurobiology. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
