Product Data Sheet
M1145
Catalog No. A62192
M1145 is a chimeric peptide that serves as a selective agonist for the galanin receptor type 2 (GAL2) with a Ki of 6.55 nM. This compound demonstrates over 90-fold increased affinity for GAL2 compared to GAL1 (Ki=587 nM) and 76-fold greater affinity relative to GalR3 (Ki=497 nM). M1145 enhances signal transduction pathways activated by galanin, making it a valuable tool for research on galanin receptor signaling and its implications in various biological processes.
Chemical Information
| Catalog Num | A62192 |
|---|---|
| M. Wt | 2774.23 |
| Formula | C128H205N37O32 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1172089-00-7 |
| Synonyms | |
| SMILES | C(=O)(N1[C@H](C(=O)N2[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N)=O)C)=O)CC(C)C)=O)C)=O)CC(C)C)=O)C)=O)CCC2)CCC1)[C@H]3N(C([C@@H](NC([C@@H](NC(=O)[C@H]4N(C(CNC([C@@H](NC([C@@H](NC([C@H](CC5=CC=C(O)C=C5)NC(CNC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC=6C=7C(NC6)=CC=CC7)NC([C@@H](NC(CNC([C@@H](NC(CNC([C@H](CCCNC(=N)N)N)=O)=O)CCCNC(=N)N)=O)=O)CC(N)=O)=O)=O)[C@@H](C)O)=O)CC(C)C)=O)CC(N)=O)=O)CO)=O)C)=O)=O)=O)CC(C)C)=O)CC(C)C)=O)=O)CCC4)[C@H](C)C)=O)CC(C)C)=O)CCC3 |
Biological Activity
| Description | M1145 is a chimeric peptide that serves as a selective agonist for the galanin receptor type 2 (GAL2) with a Ki of 6.55 nM. This compound demonstrates over 90-fold increased affinity for GAL2 compared to GAL1 (Ki=587 nM) and 76-fold greater affinity relative to GalR3 (Ki=497 nM). M1145 enhances signal transduction pathways activated by galanin, making it a valuable tool for research on galanin receptor signaling and its implications in various biological processes. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
