Product Data Sheet

RFRP-1(human)

Catalog No. A62203

main product photo
RFRP-1 (human) is a potent Neuropeptide FF (NPFF) receptor agonist that targets human gonadotropin-releasing hormone (GnRH) neurons and gonadotropes, effectively inhibiting gonadotropin release. This compound demonstrates high affinity for the NPFF receptors, with EC50 values of 0.0011 nM for NPFF2 and 29 nM for NPFF1. RFRP-1 (human) is valuable in research applications related to hormonal regulation and neuroendocrine signaling.
Chemical Information
Catalog NumA62203
M. Wt1428.70
FormulaC67H101N19O14S
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.311309-25-8
Synonyms
SMILESC(N[C@H](C(N[C@H](C(N[C@@H](CC1=CC=CC=C1)C(N)=O)=O)CCCNC(=N)N)=O)CC(C)C)(=O)[C@H]2N(C([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC3=CC=CC=C3)NC([C@@H](NC([C@@H](NC(=O)[C@H]4N(C([C@H](CCSC)N)=O)CCC4)CC5=CN=CN5)=O)CO)=O)=O)C)=O)CC(N)=O)=O)CC(C)C)=O)CCC2
Biological Activity
DescriptionRFRP-1 (human) is a potent Neuropeptide FF (NPFF) receptor agonist that targets human gonadotropin-releasing hormone (GnRH) neurons and gonadotropes, effectively inhibiting gonadotropin release. This compound demonstrates high affinity for the NPFF receptors, with EC50 values of 0.0011 nM for NPFF2 and 29 nM for NPFF1. RFRP-1 (human) is valuable in research applications related to hormonal regulation and neuroendocrine signaling.
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SHIPPING AND STORAGE
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