Product Data Sheet
Naldemedine tosylate
Catalog No. A62327
Naldemedine tosylate is a selective μ-opioid receptor antagonist, classified as a peripherally acting mu-opioid receptor antagonist (PAMORA). It exhibits high binding affinities for human μ-, δ-, and κ-opioid receptors, making it a valuable reagent for studying opioid-related pathways. Its primary application includes research on opioid-induced constipation (OIC). Additionally, Naldemedine tosylate has the potential to interact with the 3CLpro protease encoded by the SARS-CoV2 genome, suggesting further avenues for investigation in viral studies.
Chemical Information
| Catalog Num | A62327 |
|---|---|
| M. Wt | 742.84 |
| Formula | C39H42N4O9S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1345728-04-2 |
| Synonyms | S-297995 tosylate |
| SMILES | O[C@@]1(CC(C(NC(C)(C2=NC(C3=CC=CC=C3)=NO2)C)=O)=C4O)[C@@]([C@@]4([H])OC5=C6O)(CC7)C5=C(C=C6)C[C@@]1([H])N7CC8CC8.CC9=CC=C(S(=O)(O)=O)C=C9 |
Biological Activity
| Description | Naldemedine tosylate is a selective μ-opioid receptor antagonist, classified as a peripherally acting mu-opioid receptor antagonist (PAMORA). It exhibits high binding affinities for human μ-, δ-, and κ-opioid receptors, making it a valuable reagent for studying opioid-related pathways. Its primary application includes research on opioid-induced constipation (OIC). Additionally, Naldemedine tosylate has the potential to interact with the 3CLpro protease encoded by the SARS-CoV2 genome, suggesting further avenues for investigation in viral studies. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
