Product Data Sheet

CR 665

Catalog No. A62342

main product photo
CR 665 is a peripherally selective κ-opioid agonist that targets the kappa opioid receptor, exhibiting an EC50 value of 10.9 nM. This compound is primarily utilized in research focused on peripheral pain mechanisms, making it a valuable tool for studying pain modulation and analgesic pathways. Its selective action offers potential for exploring new analgesic therapies with reduced central side effects.
Chemical Information
Catalog NumA62342
M. Wt671.83
FormulaC36H49N9O4
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.228546-92-7
SynonymsJNJ 38488502; FE 200665
SMILES[C@@H](CC1=CC=CC=C1)(C(N[C@@H](C(N[C@@H](C(NCC=2C=CN=CC2)=O)CCCNC(=N)N)=O)CCCC)=O)NC([C@@H](CC3=CC=CC=C3)N)=O
Biological Activity
DescriptionCR 665 is a peripherally selective κ-opioid agonist that targets the kappa opioid receptor, exhibiting an EC50 value of 10.9 nM. This compound is primarily utilized in research focused on peripheral pain mechanisms, making it a valuable tool for studying pain modulation and analgesic pathways. Its selective action offers potential for exploring new analgesic therapies with reduced central side effects.
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SHIPPING AND STORAGE
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