Product Data Sheet
J-113397
Catalog No. A62344
J-113397 is a potent and selective nonpeptidyl antagonist of the ORL1 receptor, exhibiting a binding affinity with a Ki of 1.8 nM for cloned human ORL1. This compound is notable for its lack of agonistic activity on other opioid receptors, making it a valuable tool for studying the physiological and pharmacological roles of the ORL1 receptor. J-113397 is applicable in research focused on pain modulation, addiction, and various neurodegenerative diseases.
Chemical Information
| Catalog Num | A62344 |
|---|---|
| M. Wt | 399.57 |
| Formula | C24H37N3O2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 256640-45-6 |
| Synonyms | |
| SMILES | O=C1N([C@H]2[C@@H](CN(CC2)CC3CCCCCCC3)CO)C4=CC=CC=C4N1CC |
Biological Activity
| Description | J-113397 is a potent and selective nonpeptidyl antagonist of the ORL1 receptor, exhibiting a binding affinity with a Ki of 1.8 nM for cloned human ORL1. This compound is notable for its lack of agonistic activity on other opioid receptors, making it a valuable tool for studying the physiological and pharmacological roles of the ORL1 receptor. J-113397 is applicable in research focused on pain modulation, addiction, and various neurodegenerative diseases. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
