Product Data Sheet
5'-Guanidinonaltrindole hydrochloride
Catalog No. A62353
5'-Guanidinonaltrindole hydrochloride is a potent and selective κ-opioid receptor antagonist, exhibiting a Ki of 0.18 nM for the human κ-opioid receptor. This compound is employed in research to explore the roles of κ-opioid receptors in pain modulation, mood disorders, and addiction pathways. Its high affinity makes it a valuable tool for studies investigating the pharmacological effects of κ-opioid receptor inhibition.
Chemical Information
| Catalog Num | A62353 |
|---|---|
| M. Wt | 544.47 |
| Formula | C27H31Cl2N5O3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 351183-88-5 |
| Synonyms | 5'-GNTI hydrochloride |
| SMILES | NC(NC1=CC2=C(NC3=C2C[C@]([C@]4([H])N(CC5CC5)CC6)(O)[C@]76[C@@]3([H])OC8=C(O)C=CC(C4)=C87)C=C1)=N.[H]Cl.[H]Cl |
Biological Activity
| Description | 5'-Guanidinonaltrindole hydrochloride is a potent and selective κ-opioid receptor antagonist, exhibiting a Ki of 0.18 nM for the human κ-opioid receptor. This compound is employed in research to explore the roles of κ-opioid receptors in pain modulation, mood disorders, and addiction pathways. Its high affinity makes it a valuable tool for studies investigating the pharmacological effects of κ-opioid receptor inhibition. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
