Product Data Sheet

LY2444296

Catalog No. A62399

main product photo
LY2444296 is a selective, orally bioavailable kappa opioid receptor (KOPR) antagonist, characterized by a high binding affinity with a Ki value of approximately 1 nM. This compound is noted for its potential to produce anti-anxiety-like effects, making it a valuable tool in the study of anxiety-related disorders and the role of KOPR in neuropsychiatric research.
Chemical Information
Catalog NumA62399
M. Wt408.44
FormulaC24H22F2N2O2
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.1346133-11-6
SynonymsFP3FBZ
SMILESO=C(N)C1=CC=C(OC2=CC=C(CN3[C@H](C4=CC=CC(F)=C4)CCC3)C=C2)C(F)=C1
Biological Activity
DescriptionLY2444296 is a selective, orally bioavailable kappa opioid receptor (KOPR) antagonist, characterized by a high binding affinity with a Ki value of approximately 1 nM. This compound is noted for its potential to produce anti-anxiety-like effects, making it a valuable tool in the study of anxiety-related disorders and the role of KOPR in neuropsychiatric research.
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