Product Data Sheet

Methyl-6-alpha-Naltrexol

Catalog No. A62404

main product photo
Methyl-6-alpha-Naltrexol is a potent mu-opioid receptor antagonist and a metabolite of Methylnaltrexone (MNTX). It primarily acts as a peripherally acting receptor antagonist within the gastrointestinal tract, making it valuable for studying opioid receptor dynamics and gastrointestinal function. This compound is useful in research focused on opioid-induced constipation and opioid receptor modulation in peripheral tissues.
Chemical Information
Catalog NumA62404
M. Wt357.44
FormulaC21H27NO4
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.116388-85-3
Synonyms
SMILESO[C@@]12[C@]3([C@@H]4[C@@H](O)CC2)C5=C(O4)C(OC)=CC=C5C[C@H]1N(CC6CC6)CC3
Biological Activity
DescriptionMethyl-6-alpha-Naltrexol is a potent mu-opioid receptor antagonist and a metabolite of Methylnaltrexone (MNTX). It primarily acts as a peripherally acting receptor antagonist within the gastrointestinal tract, making it valuable for studying opioid receptor dynamics and gastrointestinal function. This compound is useful in research focused on opioid-induced constipation and opioid receptor modulation in peripheral tissues.
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