Product Data Sheet
[Arg14,Lys15]Nociceptin
Catalog No. A62473
[Arg14,Lys15]Nociceptin is a highly potent and selective agonist of the NOP receptor (also known as ORL1 or OP4), exhibiting an EC50 of 1 nM. This compound demonstrates exceptional specificity for the NOP receptor, with IC50 values of 0.32 nM for NOP and significantly higher values for μ (280 nM), δ (>10,000 nM), and κ (1500 nM) opioid receptors. [Arg14,Lys15]Nociceptin is valuable for research applications exploring pain modulation, neuropharmacology, and the role of nociceptin in various physiological processes.
Chemical Information
| Catalog Num | A62473 |
|---|---|
| M. Wt | 1909.16 |
| Formula | C82H137N31O22 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 236098-40-1 |
| Synonyms | |
| SMILES | [C@H](CC1=CC=CC=C1)(C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CCC(N)=O)C(O)=O)=O)CC(N)=O)=O)CCCCN)=O)CCCNC(=N)N)=O)CCCCN)=O)CCCNC(=N)N)=O)C)=O)CO)=O)CCCCN)=O)CCCNC(=N)N)=O)C)=O)=O)[C@@H](C)O)=O)NC(CNC(CNC([C@H](CC2=CC=CC=C2)N)=O)=O)=O |
Biological Activity
| Description | [Arg14,Lys15]Nociceptin is a highly potent and selective agonist of the NOP receptor (also known as ORL1 or OP4), exhibiting an EC50 of 1 nM. This compound demonstrates exceptional specificity for the NOP receptor, with IC50 values of 0.32 nM for NOP and significantly higher values for μ (280 nM), δ (>10,000 nM), and κ (1500 nM) opioid receptors. [Arg14,Lys15]Nociceptin is valuable for research applications exploring pain modulation, neuropharmacology, and the role of nociceptin in various physiological processes. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
