Product Data Sheet

Niravoline

Catalog No. A62493

main product photo
Niravoline is an arginine vasopressin (AVP) release inhibitor and a selective kappa opioid receptor agonist. This compound is notable for inducing a pure water diuresis effect while minimizing electrolyte loss. Additionally, Niravoline has demonstrated efficacy in reducing brain edema following transient forebrain ischemia in rodent models, making it a valuable tool for research in neuroprotection and fluid balance mechanisms.
Chemical Information
Catalog NumA62493
M. Wt379.45
FormulaC22H25N3O3
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.130610-93-4
SynonymsRU51599
SMILESO=C(N([C@@H]1[C@@H](N2CCCC2)CC3=C1C=CC=C3)C)CC4=CC=CC([N+]([O-])=O)=C4
Biological Activity
DescriptionNiravoline is an arginine vasopressin (AVP) release inhibitor and a selective kappa opioid receptor agonist. This compound is notable for inducing a pure water diuresis effect while minimizing electrolyte loss. Additionally, Niravoline has demonstrated efficacy in reducing brain edema following transient forebrain ischemia in rodent models, making it a valuable tool for research in neuroprotection and fluid balance mechanisms.
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SHIPPING AND STORAGE
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