Product Data Sheet
σ1 Receptor/μ Opioid receptor modulator 2
Catalog No. A62499
σ1 Receptor/μ Opioid receptor modulator 2 is a dual μ-opioid receptor (μOR) agonist and σ1 receptor (σ1R) antagonist. It demonstrates potent μOR agonistic activity with an EC50 value of 0.6 ± 0.2 nM and effective σ1R inhibitory activity at a Ki of 363.7 ± 5.6 nM. This compound exhibits significant analgesic effects in multiple preclinical pain models, making it a valuable tool for research in pain management and opioid receptor pharmacology.
Chemical Information
| Catalog Num | A62499 |
|---|---|
| M. Wt | 365.51 |
| Formula | C23H31N3O |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 3009018-61-2 |
| Synonyms | |
| SMILES | O=C(N(C1=CC=CC=N1)CC(N2CCC(CC2)C3=CC=CC=C3)CC)CC |
Biological Activity
| Description | σ1 Receptor/μ Opioid receptor modulator 2 is a dual μ-opioid receptor (μOR) agonist and σ1 receptor (σ1R) antagonist. It demonstrates potent μOR agonistic activity with an EC50 value of 0.6 ± 0.2 nM and effective σ1R inhibitory activity at a Ki of 363.7 ± 5.6 nM. This compound exhibits significant analgesic effects in multiple preclinical pain models, making it a valuable tool for research in pain management and opioid receptor pharmacology. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
