Product Data Sheet
MDAN-21
Catalog No. A62519
MDAN-21 is a bivalent ligand that targets the μ-opioid receptor as an agonist and the δ-opioid receptor as an antagonist. This compound exhibits significant analgesic properties, demonstrating effectiveness in reducing pain without the development of tolerance in preclinical mouse models. Additionally, MDAN-21 has shown potential in mitigating morphine withdrawal symptoms in dependent primates and alleviating abnormal pain responses in studies involving rhesus monkeys. It serves as a valuable tool for research on allodynia and pain modulation.
Chemical Information
| Catalog Num | A62519 |
|---|---|
| M. Wt | 1058.22 |
| Formula | C58H71N7O12 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 873573-64-9 |
| Synonyms | |
| SMILES | O[C@]12[C@]34[C@](OC5=C(O)C=CC(C[C@@]2([H])N(CC4)CC6CC6)=C53)([H])C7=C(C8=CC=CC(NC(COCC(NCCCCCCCNC(COCC(N[C@@H]9[C@@]%10([H])[C@]%11%12C%13=C(C[C@](N(CC%12)C)([H])[C@@]%11(CC9)O)C=CC(O)=C%13O%10)=O)=O)=O)=O)=C8N7)C1 |
Biological Activity
| Description | MDAN-21 is a bivalent ligand that targets the μ-opioid receptor as an agonist and the δ-opioid receptor as an antagonist. This compound exhibits significant analgesic properties, demonstrating effectiveness in reducing pain without the development of tolerance in preclinical mouse models. Additionally, MDAN-21 has shown potential in mitigating morphine withdrawal symptoms in dependent primates and alleviating abnormal pain responses in studies involving rhesus monkeys. It serves as a valuable tool for research on allodynia and pain modulation. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
