Loxicodegol
Catalog No. A62525

Loxicodegol is a selective mu-opioid agonist with unique structural features that enhance its long-acting, orally active profile while limiting its penetration across the blood-brain barrier relative to conventional mu-opioid agonists. This compound demonstrates significant potential for pain management applications, providing an innovative approach to opioid therapy with reduced central nervous system side effects. Its pharmacological properties make it a valuable tool for research into opioid-related analgesic mechanisms and the assessment of therapeutic strategies in chronic pain conditions.
Chemical Information
| Catalog Num | A62525 |
|---|---|
| M. Wt | 595.72 |
| Formula | C31H49NO10 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1211231-76-3 |
| Synonyms | Oxycodegol; NKTR-181 |
| SMILES | O[C@@]1(CC[C@H](OCCOCCOCCOCCOCCOCCOC)[C@]2([H])OC3=C4OC)[C@]52C3=C(C=C4)C[C@@]1([H])N(C)CC5 |
Biological Activity
| Description | Loxicodegol is a selective mu-opioid agonist with unique structural features that enhance its long-acting, orally active profile while limiting its penetration across the blood-brain barrier relative to conventional mu-opioid agonists. This compound demonstrates significant potential for pain management applications, providing an innovative approach to opioid therapy with reduced central nervous system side effects. Its pharmacological properties make it a valuable tool for research into opioid-related analgesic mechanisms and the assessment of therapeutic strategies in chronic pain conditions. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.


