Product Data Sheet
Trap-101 hydrochloride
Catalog No. A62540
Trap-101 hydrochloride is a potent and selective antagonist of the nociceptin/orphanin FQ peptide (NOP) receptor. It demonstrates a strong competitive binding affinity, as evidenced by GTPγ35S binding assays in CHOhNOP membranes, with pKi values of 8.65 for NOP and significantly lower values for classical opioid receptors. Trap-101 has been shown to alleviate motor deficits in rat models of Parkinson's disease, positioning it as a valuable tool for studying nervous system disorders and their underlying mechanisms.
Chemical Information
| Catalog Num | A62540 |
|---|---|
| M. Wt | 434.01 |
| Formula | C24H36ClN3O2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1216621-00-9 |
| Synonyms | |
| SMILES | O=C1N(CC)C2=CC=CC=C2N1C3=C(CO)CN(CC4CCCCCCC4)CC3.[H]Cl |
Biological Activity
| Description | Trap-101 hydrochloride is a potent and selective antagonist of the nociceptin/orphanin FQ peptide (NOP) receptor. It demonstrates a strong competitive binding affinity, as evidenced by GTPγ35S binding assays in CHOhNOP membranes, with pKi values of 8.65 for NOP and significantly lower values for classical opioid receptors. Trap-101 has been shown to alleviate motor deficits in rat models of Parkinson's disease, positioning it as a valuable tool for studying nervous system disorders and their underlying mechanisms. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
