Product Data Sheet
AZD-2327
Catalog No. A62555
AZD-2327 is a potent and selective agonist of the δ-opioid receptor. It demonstrates high affinity with Ki values of 0.49 nM and 0.75 nM for the C27 and F27 isoforms, respectively, and effective concentration EC50 values of 24 nM and 9.2 nM. AZD-2327 is more than 1000-fold selective over human μ- and κ-opioid receptor subtypes, as well as over 130 other receptors and channels. This compound exhibits notable antidepressant and anxiolytic properties, making it valuable for research in neurological disorders.
Chemical Information
| Catalog Num | A62555 |
|---|---|
| M. Wt | 474.61 |
| Formula | C29H35FN4O |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 875647-81-7 |
| Synonyms | |
| SMILES | CCN(CC)C(C(C=C1)=CC=C1[C@H](C2=CC(N)=CC=C2)N3CCN(CC4=CC=C(F)C=C4)CC3)=O |
Biological Activity
| Description | AZD-2327 is a potent and selective agonist of the δ-opioid receptor. It demonstrates high affinity with Ki values of 0.49 nM and 0.75 nM for the C27 and F27 isoforms, respectively, and effective concentration EC50 values of 24 nM and 9.2 nM. AZD-2327 is more than 1000-fold selective over human μ- and κ-opioid receptor subtypes, as well as over 130 other receptors and channels. This compound exhibits notable antidepressant and anxiolytic properties, making it valuable for research in neurological disorders. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
