Product Data Sheet
Fluorphine
Catalog No. A62565
Fluorphine is a potent μ-opioid receptor (MOR) ligand that exhibits a binding affinity with a Ki value of 12.5 nM. This compound demonstrates biological activity by promoting GTPγS binding with an EC50 of 75 nM and facilitating β-arrestin 2 recruitment with an EC50 of 377 nM. Fluorphine is primarily used in research to investigate opioid signaling pathways and their physiological effects, including respiratory depression.
Chemical Information
| Catalog Num | A62565 |
|---|---|
| M. Wt | 339.41 |
| Formula | C20H22FN3O |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 6440-42-2 |
| Synonyms | |
| SMILES | O=C1NC2=C(N1C3CCN(C(C)C4=CC=C(C=C4)F)CC3)C=CC=C2 |
Biological Activity
| Description | Fluorphine is a potent μ-opioid receptor (MOR) ligand that exhibits a binding affinity with a Ki value of 12.5 nM. This compound demonstrates biological activity by promoting GTPγS binding with an EC50 of 75 nM and facilitating β-arrestin 2 recruitment with an EC50 of 377 nM. Fluorphine is primarily used in research to investigate opioid signaling pathways and their physiological effects, including respiratory depression. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
