Product Data Sheet
Ac-RYYRWK-NH2 TFA
Catalog No. A62578
Ac-RYYRWK-NH2 TFA serves as a potent and selective partial agonist for the nociceptin receptor (NOP). It exhibits significant binding affinity, with a Kd of 0.071 nM for rat cortical membranes (ORL1), while demonstrating no affinity for μ-, κ-, or δ-opioid receptors. This compound is valuable for research investigating nociceptin signaling pathways and their implications in pain modulation and various neurological disorders.
Chemical Information
| Catalog Num | A62578 |
|---|---|
| M. Wt | 1126.19 |
| Formula | C51H70F3N15O11 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 408305-09-9 |
| Synonyms | |
| SMILES | OC(=O)C(F)(F)F.CC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCCN)C(N)=O |
Biological Activity
| Description | Ac-RYYRWK-NH2 TFA serves as a potent and selective partial agonist for the nociceptin receptor (NOP). It exhibits significant binding affinity, with a Kd of 0.071 nM for rat cortical membranes (ORL1), while demonstrating no affinity for μ-, κ-, or δ-opioid receptors. This compound is valuable for research investigating nociceptin signaling pathways and their implications in pain modulation and various neurological disorders. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
