CTOP
Catalog No. A62611

CTOP is a potent and highly selective μ-opioid receptor antagonist. It effectively counteracts the acute analgesic effects of morphine and mitigates hypermotility associated with opioid administration. Additionally, CTOP has been shown to enhance extracellular dopamine levels in the nucleus accumbens and dose-dependently increase locomotor activity, making it a valuable tool for research on opioid receptor functions and dopamine activity in the context of pain and addiction studies.
Chemical Information
| Catalog Num | A62611 |
|---|---|
| M. Wt | 1062.26 |
| Formula | C50H67N11O11S2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 103429-31-8 |
| Synonyms | |
| SMILES | C(C=1C=2C(NC1)=CC=CC2)[C@H]3NC(=O)[C@H](CC4=CC=C(O)C=C4)NC(=O)[C@@H](NC([C@@H](CC5=CC=CC=C5)N)=O)CSSC(C)(C)[C@@H](C(N[C@@H]([C@@H](C)O)C(N)=O)=O)NC(=O)[C@]([C@@H](C)O)(NC(=O)[C@H](CCCN)NC3=O)[H] |
Biological Activity
| Description | CTOP is a potent and highly selective μ-opioid receptor antagonist. It effectively counteracts the acute analgesic effects of morphine and mitigates hypermotility associated with opioid administration. Additionally, CTOP has been shown to enhance extracellular dopamine levels in the nucleus accumbens and dose-dependently increase locomotor activity, making it a valuable tool for research on opioid receptor functions and dopamine activity in the context of pain and addiction studies. |
|---|
RETURN POLICY
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Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.


