Product Data Sheet
ICI-204448 free acid
Catalog No. A62640
ICI-204448 free acid is a potent κ-opioid agonist that demonstrates limited central nervous system penetration. It effectively displaces the binding of the kappa-opioid ligand ^3H-bremazocine from guinea pig cerebellum membranes, making it a valuable tool for exploring κ-opioid receptor interactions. This compound is useful in research applications focused on pain modulation, neuropsychiatric disorders, and the pharmacological profiling of κ-opioid receptors.
Chemical Information
| Catalog Num | A62640 |
|---|---|
| M. Wt | 465.37 |
| Formula | C23H26Cl2N2O4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 125190-72-9 |
| Synonyms | |
| SMILES | O=C(COC1=CC=CC(C(CN2CCCC2)N(C)C(CC3=CC=C(C(Cl)=C3)Cl)=O)=C1)O |
Biological Activity
| Description | ICI-204448 free acid is a potent κ-opioid agonist that demonstrates limited central nervous system penetration. It effectively displaces the binding of the kappa-opioid ligand ^3H-bremazocine from guinea pig cerebellum membranes, making it a valuable tool for exploring κ-opioid receptor interactions. This compound is useful in research applications focused on pain modulation, neuropsychiatric disorders, and the pharmacological profiling of κ-opioid receptors. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
