Product Data Sheet

CVN766

Catalog No. A62716

main product photo
CVN766 is an orally active orexin-1 receptor antagonist, exhibiting an IC50 of 8 nM for OX1R and greater than 10 μM for OX2R, indicating selectivity. This compound demonstrates effective blood-brain barrier permeability, making it suitable for neurological studies. CVN766 is primarily utilized in research related to schizophrenia, providing insights into the role of orexin receptors in neuropsychiatric disorders.
Chemical Information
Catalog NumA62716
M. Wt446.43
FormulaC20H21F3N8O
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.1803557-42-7
Synonyms
SMILESCCC1=NC(C(F)(F)F)=CN=C1N[C@@H]2[C@@H](NC(C3=NC=CC=C3N4N=CC=N4)=O)CCC2
Biological Activity
DescriptionCVN766 is an orally active orexin-1 receptor antagonist, exhibiting an IC50 of 8 nM for OX1R and greater than 10 μM for OX2R, indicating selectivity. This compound demonstrates effective blood-brain barrier permeability, making it suitable for neurological studies. CVN766 is primarily utilized in research related to schizophrenia, providing insights into the role of orexin receptors in neuropsychiatric disorders.
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