Product Data Sheet

Cleminorexton

Catalog No. A62733

main product photo
Cleminorexton is an orally active agonist of the orexin-2 receptor (OX2R), exhibiting a pEC50 value between 9 and 10.4. This compound is primarily utilized in research related to narcolepsy and other disorders characterized by orexin deficiency and excessive daytime sleepiness. Its modulation of OX2R activity makes it a valuable tool for studying sleep-wake regulation and potential therapeutic interventions.
Chemical Information
Catalog NumA62733
M. Wt512.52
FormulaC24H24F4N2O4S
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2980518-93-0
Synonyms
SMILESFC1=C(C2=C(C(F)=CC(F)=C2)OCCC3=O)C=CC=C1C[C@]4([H])N3CCC[C@@]4(NS(C5(CC5)F)(=O)=O)[H]
Biological Activity
DescriptionCleminorexton is an orally active agonist of the orexin-2 receptor (OX2R), exhibiting a pEC50 value between 9 and 10.4. This compound is primarily utilized in research related to narcolepsy and other disorders characterized by orexin deficiency and excessive daytime sleepiness. Its modulation of OX2R activity makes it a valuable tool for studying sleep-wake regulation and potential therapeutic interventions.
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