Product Data Sheet
PSB-1737
Catalog No. A62758
PSB-1737 is a selective agonist of the GPR17 receptor, exhibiting an EC50 of 270 nM for human GPR17, with significantly reduced activity on murine GPR17 (EC50 > 10 μM). This compound does not exhibit significant inhibition at the glycine binding site of NMDA receptors, nor does it show notable activity on P2Y receptor subtypes. PSB-1737 is valuable for research in the context of demyelinating diseases, such as multiple sclerosis, and inflammatory-related anemia.
Chemical Information
| Catalog Num | A62758 |
|---|---|
| M. Wt | 325.32 |
| Formula | C18H15NO5 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 139896-80-3 |
| Synonyms | |
| SMILES | O=C(C1=C(CCC(O)=O)C2=C(C=C(C=C2)OC3=CC=CC=C3)N1)O |
Biological Activity
| Description | PSB-1737 is a selective agonist of the GPR17 receptor, exhibiting an EC50 of 270 nM for human GPR17, with significantly reduced activity on murine GPR17 (EC50 > 10 μM). This compound does not exhibit significant inhibition at the glycine binding site of NMDA receptors, nor does it show notable activity on P2Y receptor subtypes. PSB-1737 is valuable for research in the context of demyelinating diseases, such as multiple sclerosis, and inflammatory-related anemia. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
