Product Data Sheet
L-372662
Catalog No. A62771
L-372662 is a potent, orally active non-peptide antagonist of the oxytocin receptor (OTR). It has a Ki value of 4.8 nM and demonstrates high affinity with Kd values of 5.8 nM for wild-type OTR and 73 nM for the [A318G] variant. This compound exhibits selectivity for OTR over the vasopressin 1a receptor (V1aR), making it a valuable tool in research applications related to neuroendocrine regulation and social behavior.
Chemical Information
| Catalog Num | A62771 |
|---|---|
| M. Wt | 586.68 |
| Formula | C33H38N4O6 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 162045-26-3 |
| Synonyms | |
| SMILES | O=C(OC1)N(C2CCN(C(C3=C(OC)C=C(OC4CCN(CC5=C(C)[N+]([O-])=CC=C5)CC4)C=C3)=O)CC2)C6=C1C=CC=C6 |
Biological Activity
| Description | L-372662 is a potent, orally active non-peptide antagonist of the oxytocin receptor (OTR). It has a Ki value of 4.8 nM and demonstrates high affinity with Kd values of 5.8 nM for wild-type OTR and 73 nM for the [A318G] variant. This compound exhibits selectivity for OTR over the vasopressin 1a receptor (V1aR), making it a valuable tool in research applications related to neuroendocrine regulation and social behavior. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
