Product Data Sheet
L-368,899
Catalog No. A62786
L-368,899 is a selective antagonist of the oxytocin (OT) receptor, exhibiting IC50 values of 8.9 nM and 26 nM in rat and human uterine tissues, respectively. This orally active compound effectively crosses the blood-brain barrier and is proven to inhibit oxytocin-stimulated uterine contractions in rat models. L-368,899 is valuable for research into preterm labor and the physiological roles of oxytocin in reproductive biology.
Chemical Information
| Catalog Num | A62786 |
|---|---|
| M. Wt | 554.77 |
| Formula | C26H42N4O5S2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 148927-60-0 |
| Synonyms | |
| SMILES | O=S(C[C@]12[C@H](C[C@@H](CC2)C1(C)C)NC([C@@H](N)CCS(C)(=O)=O)=O)(N3CCN(C4=C(C=CC=C4)C)CC3)=O |
Biological Activity
| Description | L-368,899 is a selective antagonist of the oxytocin (OT) receptor, exhibiting IC50 values of 8.9 nM and 26 nM in rat and human uterine tissues, respectively. This orally active compound effectively crosses the blood-brain barrier and is proven to inhibit oxytocin-stimulated uterine contractions in rat models. L-368,899 is valuable for research into preterm labor and the physiological roles of oxytocin in reproductive biology. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
