Product Data Sheet
AR-C118925XX
Catalog No. A62809
AR-C118925XX is a selective antagonist of the P2Y2 receptor. It effectively inhibits ATP-induced production of interleukin-6 (IL-6) and the phosphorylation of p38 MAPK, key players in inflammatory responses. In vivo studies demonstrate that AR-C118925XX also suppresses Bleomycin-induced dermal fibrosis in mice and inhibits ATP-mediated tumor growth, making it valuable for research in fibrosis, inflammation, and cancer biology.
Chemical Information
| Catalog Num | A62809 |
|---|---|
| M. Wt | 537.59 |
| Formula | C28H23N7O3S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 216657-60-2 |
| Synonyms | |
| SMILES | O=C(C1=CC=C(CN2C=C(C3C4=CC=C(C)C=C4C=CC5=CC(C)=CC=C53)C(NC2=O)=S)O1)NC6=NN=NN6 |
Biological Activity
| Description | AR-C118925XX is a selective antagonist of the P2Y2 receptor. It effectively inhibits ATP-induced production of interleukin-6 (IL-6) and the phosphorylation of p38 MAPK, key players in inflammatory responses. In vivo studies demonstrate that AR-C118925XX also suppresses Bleomycin-induced dermal fibrosis in mice and inhibits ATP-mediated tumor growth, making it valuable for research in fibrosis, inflammation, and cancer biology. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
