Product Data Sheet
P2Y1/P2Y12 antagonist-1
Catalog No. A62827
P2Y1/P2Y12 antagonist-1 is a dual inhibitor targeting the P2Y1 and P2Y12 receptors, providing significant antiplatelet activity. This compound effectively inhibits ADP-induced platelet aggregation in rabbit plasma, demonstrating an IC50 value of 4.23 μM. Additionally, P2Y1/P2Y12 antagonist-1 shows potent inhibitory effects in a rat thrombosis model, making it a valuable tool for research on platelet function and related cardiovascular conditions.
Chemical Information
| Catalog Num | A62827 |
|---|---|
| M. Wt | 386.40 |
| Formula | C22H18N4O3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2738381-94-5 |
| Synonyms | |
| SMILES | N#CC1=CC=C(CON2C(C3=CC(C#N)=CC=C3)=NC(C)=C2C(OCC)=O)C=C1 |
Biological Activity
| Description | P2Y1/P2Y12 antagonist-1 is a dual inhibitor targeting the P2Y1 and P2Y12 receptors, providing significant antiplatelet activity. This compound effectively inhibits ADP-induced platelet aggregation in rabbit plasma, demonstrating an IC50 value of 4.23 μM. Additionally, P2Y1/P2Y12 antagonist-1 shows potent inhibitory effects in a rat thrombosis model, making it a valuable tool for research on platelet function and related cardiovascular conditions. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
